Biologic age assessment using digital PCR: Validation of a 7-target methylation panel

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Speaker: Dr. Céline Bourgne, Ph.D., Hospital Biological Engineer at CHU Estaing (France). Dr. Bourgne’s research centers on the BIO-TIMER Study, which explores the integration of biological age and individual frailty, to enhance cancer management through targeted therapies.

Highlights 

• Biological Age: A critical health indicator with potential applications in cancer treatment stratification, the biological age represents physiological function and overall health, influenced by lifestyle, environment, and genetics.
• Methylation Analysis clocks are widely studied for aging assessments, with CpG methylation patterns predicting biological age with high accuracy.
• Development of a 7-plex methylation panel: Leveraging the Crystal Flex Probes technology from Stilla Technologies, Celine and her team are currently validating a 21-probe assay to quantify the methylation of 7 different DNA sites accurately.
• Advantage of the Stilla Technologies custom assay: The assay design is simplified and allows unmatched high-plex capabilities, while dPCR technology provides precision with single-molecule resolution and absolute quantification.

This 20-minute webinar are for researchers interested in DNA methylation and its correlation with increased disease risk, as well as for dPCR users in need of customizable assays.

Learn more about Stilla Crystal Flex Probes with our Commercial Brochure & our Application Note, ESR1 12-plex assay.